Tuesday, November 29, 2011

A timeline of the Alzheimer’s disease

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(some key milestones)
1991: The NIA established the Alzheimer’s Disease Cooperative Study, a nationwide medical network to facilitate clinical research and conduct federally funded clinical trials.
1993: Researchers identify APOE-e4, a form of the apolipoprotein-E (APOE) gene on chromosome 19, as the first gene that raises risk for Alzheimer’s.
1993: The Food and Drug Administration approves tacrine (Cognex) as the first drug specifically targeting Alzheimer’s memory and thinking symptoms. Four more drugs are approved over the next 10 years.
1995: Researchers announce the first transgenic mouse model that developed Alzheimer’s-like brain pathology after it was inserted with one of the human genes linked to a rare form of Alzheimer’s.
1999: Reports are published showing that injecting transgenic “Alzheimer’s” mice with beta-amyloid prevents them from developing plaques and other Alzheimer’s-like brain changes. Continue to read: ajc.com


L-arginine changes nothing for fit young men at rest

Supplements of the amino acid L-arginine may not produce metabolic or hormonal enhancement for fit young men at rest, says a new study from Canada. Read more: nutraingredients-usa.com
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