Alzheimer’s Disease Spreads Through Linked Nerve Cells

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(  axons that branch between and connect neurons )

Alzheimer's disease and other forms of dementia may spread within nerve networks in the brain by moving directly between connected neurons, instead of in other ways proposed by scientists, such as by propagating in all directions, according to researchers who report the finding in the March 22 edition of the journal Neuron. The finding, based on new magnetic resonance imaging research (MRI), raises hopes that physicians may be able to use MRI to predict the course of dementias -- depending on where within an affected network degenerative damage is first discovered -- and that researchers may use these predicted outcomes to determine whether a new treatment is working. Network modeling combined with functional MRI might serve as an intermediate biomarker to gauge drug efficacy in clinical trials before behavioral changes become measurable, according to Seeley.

"Our next goal is to further develop methods to predict disease progression, using these models to create a template for how disease will progress in the brain of an affected individual," Seeley said. "Already this work suggests that if we know the wiring diagram in a healthy brain, we can predict where the disease is going to go next. Once we can predict how the network will change over time we can predict how the patient's behavior will change over time and we can monitor whether a potential therapy is working". Continue to read: sciencedaily.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

TODAY'S PHOTO

Coconut oil and Alzheimer’s

Coconut is being studied today for its ketone content because preliminary research appears to suggest that ketones are useful in preventing and in helping cure Alzheimer’s dementia. Read more: coconut oil good for Alzheimer’s

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