Saturday, March 3, 2012

Gene expression associated with Alzheimer's disease

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(  a gene therapy approach to reduce the levels of HDAC2 )
A repression of gene activity in the brain appears to be an early event affecting people with Alzheimer's disease, researchers funded by the National Institutes of Health have found. In mouse models of Alzheimer's disease, this epigenetic blockade and its effects on memory were treatable.
"These findings provide a glimpse of the brain shutting down the ability to form new memories gene by gene in Alzheimer's disease, and offer hope that we may be able to counteract this process," said Roderick Corriveau, Ph.D., a program director at NIH's National Institute of Neurological Disorders and Stroke (NINDS), which helped fund the research.
Dr. Li-Huei Tsai and her team at the Massachusetts Institute of Technology and the Howard Hughes Medical Institute found that a protein called histone deacetylase 2 (HDAC2) accumulates in the brain early in the course of Alzheimer's disease in mouse models and in people with the disease. Continue to read: consumeraffairs.com


Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy


High dose omega-3 may benefit early communicative development


A fish oil supplement enriched with DHA may benefit early communicative development in infants, says the first randomized controlled trial testing high dose omega-3 on brain development in non-premature infants. Read more: nutraingredients.com 

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