'Brain Pacemaker' Improves Memory in Alzheimer's Patients

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 Insertion of a deep brain stimulator (DBS), a device similar to a pacemaker for the brain, may improve memory and function for patients with Alzheimer’s disease.Recent research showed that after implanting a DBS in six patients with Alzheimer's, half of the patients had either improved memory, or a slower rate of decline.

"We showed that not only is this a safe procedure, but that the evidence is there to warrant a bigger trial," according to Dr. Andres Lozano and colleagues at Toronto Western Hospital, who conducted the research. "Any amount of time that extends quality of life and quality years to someone with Alzheimer's may be a benefit." Alzheimer's disease (AD) is the most common form of dementia among older people, and affects more than five million Americans, according to the Alzheimer's Organization. 

"Alzheimer's disease (AD) is characterized by functional impairment in the neural elements and circuits underlying cognitive and memory functions," according to Lozano. Initially, affected individuals have mild memory problems, which progress over time, to the point of needing total care. Other, later symptoms can include anxiety, wandering, and aggression. No treatment can stop the disease. However, some drugs, may delay the progression of the disease, and others, including antipsychotics, may help treat certain symptoms for a limited time.

Lozano and his team investigated the theory that electrical stimulation of structures deep in the brain, including the hypothalamus, might improve symptoms by enrolling six willing participants with early signs of Alzheimer's in their study. Read more: livescience.com

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