Food supplementation and Alzheimer’s
( you are what you eat )
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Numerous lines of evidence indicate that chronic inflammation plays a major role in the development of various neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, brain tumor, and meningitis. Why these diseases are more common among people from some countries than others is not fully understood, but lifestyle factors have been linked to the development of neurodegenerative diseases. For example, the incidence of certain neurodegenerative diseases among people living in the Asian subcontinent, where people regularly consume spices, is much lower than in countries of the western world. Extensive research over the last 10 years has indicated that nutraceuticals derived from such spices as turmeric, red pepper, black pepper, licorice, clove, ginger, garlic, coriander, and cinnamon target inflammatory pathways, thereby may prevent neurodegenerative diseases. How these nutraceuticals modulate various pathways and how they exert neuroprotection are the focus of this review. Mol Neurobiol
Multiple epidemiological studies examining fish consumption and tissue DHA levels are cited to support the proposition that increased DHA intake might protect the brain from the devastating effects of dementia. However, epidemiological studies cannot tease apart an isolated contribution of DHA as the determining beneficial factor in fish and seafood. Fish are an important source of trace minerals, such as iodine and selenium, and increased selenium associated with fish consumption may also contribute to the health benefits ascribed to DHA. Fish are a major source of vitamin D, which through neurotrophic, anti-inflammatory, and neuroprotective effects may work synergistically with DHA to protect the brain. Other omega-3 fatty acids in addition to DHA are also found in fish. These essential fats, including eicosapentaenoic acid (EPA), can themselves have important vascular and anti-inflammatory effects. DHA might interfere with the metabolism of other essential fatty acids from shorter precursors. For example, DHA-only supplements may decrease the abundance of EPA by inhibiting enzymatic conversion from alpha-linolenic acid. It would be interesting to know if the DHA given in this clinical trial induced changes in other essential fatty acids. Read more: jama.ama-assn.org
Probiotic - a tool to treat ulcers
Spanish researchers have described a strain of probiotic bacteria as a new “promising tool” in the treatment of ulcers caused by Helicobacter pylori in their report published in the latest edition of the journal Applied and Environmental Microbiology. Read more: nutraingredients.com
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