Sunday, April 15, 2012

GE Healthcare Strengthens R&D Efforts in Alzheimer’s


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(  to diagnose the level of severity )
Professor Hiroyuki Arai of the Institute of Development, Aging and Cancer at Tohoku University is the leading domestic researcher on Alzheimer’s and the first person in the world to succeed in detecting tau proteins in cerebrospinal fluid and argue for their significance as surrogate biomarker. Dr. Arai stresses the crucial nature of tau imaging in Alzheimer’s diagnoses: “Research data on PET imaging of amyloid are currently being accumulated, and the thinking now is that if we can conduct additional tau PET imaging on healthy subjects who have tested positive in amyloid PET exams, it will become possible to identify those with high risk of converting to Alzheimer’s. This could lead to diagnoses of pre-clinical stage Alzheimer’s disease’, which may enable prevention before the onset of symptoms.”


As of 2010, there were a total of approximately 35.6 million confirmed cases of Alzheimer’s disease worldwide, and projections indicate that the total will reach 115.4 million cases by 2050. 1 In Japan, which is leading the world in terms of the advance of population aging, there were approximately 2 million cases in 2010, with a projected 3.25 million expected by 2020 2 . Alzheimer’s is thought to be caused by accumulations within the brain of beta amyloid and tau proteins. Beta amyloid plaques are thought to begin accumulating within the brain 30 years before symptoms appear, and tau proteins ten years prior.



“The collaboration we are announcing today is part of our ongoing effort to understand and identify Alzheimer’s disease in its very early stages,” said Pascale Witz, CEO of GE Healthcare Medical Diagnostics.


“The combination of our different business offerings positions us well to offer an integrated global diagnostics solution for the next generation of therapies. We are working with pharma to understand their strategic needs and design solutions accordingly”. Continue to readpr-inside.com


Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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