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Light to moderate drinking seems to reduce the risk for dementia and cognitive decline, according to a new study published in the August issue of Neuropsychiatric Disease and Treatment.
A meta-analysis of 143 studies on the effects of alcohol on the brain showed that moderate drinking, defined as no more than 2 drinks a day for a man and no more than 1 drink a day for a woman, reduced the risk for Alzheimer's disease and other forms of dementia by 23%."It doesn't seem to matter if it's beer, wine, or spirits, as long as the drinking was moderate," Edward J. Neafsey, PhD, from the Department of MolecularPharmacology and Therapeutics at Loyola University Medical Center, Maywood, Illinois, told Medscape Medical News. Dr. Neafsey and coauthor Michael A. Collins, PhD, became interested in seeing whether alcohol might be protective of human brains after their experiments showed that rat brains exposed to low doses of alcohol for a few days demonstrated resiliency when subsequently treated with a toxin.
The researchers reviewed studies dating from 1977 up to the present. The studies fell into 2 categories: those that provided ratios of risk between drinkers and nondrinkers (n = 74) and those that rated cognition in drinkers as "better," "no different," or "worse" than cognition in nondrinkers (n = 69). "If the rat brain slices were treated for 5 or 6 days with low alcohol and then the toxin was administered, there was hardly any damage, whereas if they didn't get the pretreatment with alcohol, there was significant damage. This led us to ask if there was anything in the human literature that would fit with this protective effect of alcohol," Dr. Neafsey explained. Continue to read: medilexicon.com
A meta-analysis of 143 studies on the effects of alcohol on the brain showed that moderate drinking, defined as no more than 2 drinks a day for a man and no more than 1 drink a day for a woman, reduced the risk for Alzheimer's disease and other forms of dementia by 23%."It doesn't seem to matter if it's beer, wine, or spirits, as long as the drinking was moderate," Edward J. Neafsey, PhD, from the Department of Molecular
The researchers reviewed studies dating from 1977 up to the present. The studies fell into 2 categories: those that provided ratios of risk between drinkers and nondrinkers (n = 74) and those that rated cognition in drinkers as "better," "no different," or "worse" than cognition in nondrinkers (n = 69). "If the rat brain slices were treated for 5 or 6 days with low alcohol and then the toxin was administered, there was hardly any damage, whereas if they didn't get the pretreatment with alcohol, there was significant damage. This led us to ask if there was anything in the human literature that would fit with this protective effect of alcohol," Dr. Neafsey explained. Continue to read: medilexicon.com
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