Subjective memory impairment in suspected cases of Alzheimer's
(hippocampal deficit)
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Scientists at Charité - Universitätsmedizin Berlin, Universitätsklinikum Bonn, and Deutsches Zentrum für Neurodegenerative Erkrankungen in Bonn succeeded for the first time in demonstrating that even in merely subjective cases of memory deterioration changes may be visible in certain brain structures. The study, published in the current issue of the Archives of General Psychiatry on August 1, supports the model whereby subjective memory impairment can be the first manifestation ofAlzheimer's disease. Although not every individual with subjective memory impairment develops Alzheimer's disease, almost every patient with Alzheimer's disease initially develops subjective memory impairment that has not been possible to objectify until now.
Alzheimer's disease is the most frequent cause of dementia. The key to dementia prevention is diagnosis as early as possible. For some years now it has been a confirmed fact that in individuals who already have a slight objective memory impairment it is possible to diagnose the onset of Alzheimer's disease by means of imaging procedures and cerebrospinal fluid tests. However, it would be even better to reveal signs of such a disease at an even earlier stage. Researchers from Bonn and Berlin have now taken an important step in this direction: They found signs of brain function disorders in individuals who merely experience a subjective deterioration in memory without any reduced performance been detectable in objective behavioral tests. Continue to read: news-medical.net
Alzheimer's disease is the most frequent cause of dementia. The key to dementia prevention is diagnosis as early as possible. For some years now it has been a confirmed fact that in individuals who already have a slight objective memory impairment it is possible to diagnose the onset of Alzheimer's disease by means of imaging procedures and cerebrospinal fluid tests. However, it would be even better to reveal signs of such a disease at an even earlier stage. Researchers from Bonn and Berlin have now taken an important step in this direction: They found signs of brain function disorders in individuals who merely experience a subjective deterioration in memory without any reduced performance been detectable in objective behavioral tests. Continue to read: news-medical.net