Alzheimer’s: the strengthening or weakening of synapses
(acetylcholine system and hippocampus)
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The key to strong nerve cell connections, or synapses, may be found in the timing as the neurotransmitter acetylcholine is released in the brain’s hippocampus, according to a mouse study. Understanding the inner workings of neuron signaling could help scientists better understand the processes of learning and memory, and lead to new treatments for disorders such as schizophrenia and Alzheimer’s.
Neurons in the hippocampus (a brain region believed to play a vital role in learning and memory) communicate with each other at synapses by releasing various neurotransmitters, such as acetylcholine and glutamate, which trigger electrical signals in nearby neurons.
Neuroscientists have been working to pinpoint which cellular processes enable humans to learn from experience and save memories, and how certain conditions, such as schizophrenia and Alzheimer’s, affect these mechanisms.
Neurons in the hippocampus (a brain region believed to play a vital role in learning and memory) communicate with each other at synapses by releasing various neurotransmitters, such as acetylcholine and glutamate, which trigger electrical signals in nearby neurons.
Neuroscientists have been working to pinpoint which cellular processes enable humans to learn from experience and save memories, and how certain conditions, such as schizophrenia and Alzheimer’s, affect these mechanisms.
Now, researchers from the National Institute of Environmental Health Sciences (NIEHS) believe they have discovered one such mechanism that synchronizes changes in the strength of synapses. Continue to read: psychcentral.com
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