Alzheimer's: prophylactic intervention
(Alzheimer's can progress at different rates)
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Curing Alzheimer’s disease may be impossible and the best hope to control the disease may require beginning treatments as much as 20 years before the onset of symptoms. It could take decades to find effective therapies for the brain-wasting disease. That is the view of Dr. Sam Gandy, a highly respected Alzheimer's expert at Mount Sinai Medical Center in New York. Writing a perspective article titled “Prevention is Better than Cure” in this week’s issue of the journal Nature, Gandy offers an argument that will likely dominate much of the discussion next week when 4,000 researchers gather in Paris for the Alzheimer’s Association’s Annual International Conference.
Gandy notes it has been more than a century since the German psychiatrist Alois Alzheimer described the condition that bears his name. Dr. Alzheimer discovered the disease in a 51-year-old woman called Auguste D. After her death, Alzheimer noticed her brain was speckled with plaques of a protein now known as amyloid-beta peptide. In recent decades, on the basis of sound evidence, many scientists have concluded that amyloid plaques play a key role in causing the devastation of Alzheimer’s disease. The pharmaceutical industry has produced drugs and vaccines designed to clear the plaques from the brain. The problem is, in a few large studies the plaque goes away, but the symptoms of the disease continue to worsen. Continue to read: msnbc.msn.com
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