Thursday, September 30, 2010

What makes a brain-healthy lifestyle 
(doing anything is better than doing nothing)
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Not too long ago, scientists believed we all start with roughly 3 trillion brain cells that, through careless decisions such as drinking alcohol and playing tackle football, we gradually kill off. Once a brain cell was lost, the brain was one man down, forever. That's a myth, we now know.

The brain is a tangled web of cells that is constantly rewiring itself, like acrobats unlinking arms and swapping partners. The brain can grow new cells to link into its intricate network, tossing a new gymnast into the act.

In the last five years, scientists have unlocked the secret to manufacturing the precious cells involved in memory and recall, the ones that light up when digging for our best friend's name or our mother's address. In experiments where mice were timed running through mazes or recalling patterns, the rodents that broke a sweat on a hamster wheel performed better. After slicing into their brains, scientists discovered why: The exercising mice had grown new brain cells.

"Exercise creates a stronger, faster brain," said Beverly Engel, program coordinator for the Alzheimer's Association in Central Florida. Patients with Parkinson's disease have regrown brain cells after just two months of physical exercise. No one knows the perfect exercise formula for brain health — some experts say 30 to 60 minutes, three times a week — but simply walking has shown benefits.
 Read more: the33tv.com



Mediterranean style diet lower risk of Alzheimer's disease
More and more evidence shows that eating a Mediterranean style diet can reduce the risk for cancerheart disease, stroke, diabetes and even dementia. You can live longer and live better by eating great food. Read morefox17online.com
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Wednesday, September 29, 2010

Amyloid protein may bring beneficial effects
(against cancer)
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Scientists at the Roskamp Institute in Sarasota, Florida, have shown that mice that naturally develop Alzheimer's are able to ward off the growth of brain cancer. In a series of experiments published in the Journal of Neuroscience, they showed that mice that spontaneously develop Alzheimer's Disease are able to dramatically reduce the growth of a human brain cancer. Brain cancers affect 612,000 people in the United States and are particularly common in children and older adults. 10,000 Americans are diagnosed each year with one of the most deadly brain tumors called malignant gliomas, the type of brain tumor tested in the study. Only about 50% of patients are alive 1 year after diagnosis, and 25% after two years despite surgical and medical treatment. Scientists believe that the cancers in the brains of the Alzheimer mice don't grow as they normally would because their blood supply is choked. It has long been known that in order to grow cancers need large blood supplies which they hijack from existing normal blood supplies. This is true of the brain cancers tested in the mice. In the normal mice without Alzheimer's Disease the cancers grew rapidly and aggressively in the brain as they do in humans. But in the mice with Alzheimer's Disease the brain cancers grew much more slowly and their blood supplies were greatly reduced.  Read more: sunherald.com



Biomedical science into nutritional strategies
Nestlé has announced the creation of two new organisations to develop personalised health science nutrition to prevent and treat health conditions such as diabetes, obesity, heart disease and Alzheimer's. Read morenutraingredients.com
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Tuesday, September 28, 2010

Promising test for Alzheimer's 
(state of confusion)
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Alzheimer's is a brain disease that causes the memory to slowly erode, eventually ending in death. When symptoms of dementia appear, it's common for patients to seek out memory centers such as the one at Johns Hopkins to find out what's going on.
Though a good medical history, a physical and cognitive tests are typically the first type of work-up a person receives, there are an increasing array of methods for evaluating brain function earlier and more accurately, says Alzheimer's Association chief medical and scientific officer Bill Thies.
Tests for biomarkers —substances in the body such as proteins that indicate underlying disease — hold promise. They include newer and more complex MRI and PET scan imaging, not widely used yet, which can measure the size of brain regions and can look for the amyloid plaques and tau tangles that are the physical hallmarks of the disease, Thies said. Genetic tests for certain "risk genes" also can be done.
The availability, accuracy and value — especially early on — of such Alzheimer's tests are subject to debate because effective treatments have yet to be found, he says. "This whole scene will change when and if we develop more effective treatments," said Ron Petersen, director of the Mayo Clinic Alzheimer's Disease Research Center. Read more: poughkeepsiejournal.com


Japanese supplement and functional food
Green tea, soy and CoQ10 are some of the best known ingredients for supplements and functional foods from Japan, but a wealth of lesser-known foodstuffs are also the subject of inquiry into their potential health benefits. Read morenutraingredients.com
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Monday, September 27, 2010

Genetic changes are involved in Alzheimer's 
(genetic and environmental risk factors)
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Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer disease (AD), the most common type of the disease. Abbreviated MTHFD1L, a gene on chromosome six, was identified in a genome-wide association study by a team of researchers led by Margaret Pericak-Vance, Ph.D., director of the John P. Hussman Institute for Human Genomics (HIHG) at the University of Miami Miller School of Medicine. Details appear September 23 in the open-access journal PLoS Genetics.
The World Health Organization estimates that there are currently 18 million people worldwide with Alzheimer's disease, and this figure is projected to nearly double to 34 million by 2025. By looking at gene variation throughout the human genomes of 2,269 subjects with late-onset AD and 3,107 without the disease, researchers were able to pinpoint small differences in the genetic sequences of people with and without AD. 

The study found that individuals with a particular variation in the gene MTHFD1L may be almost twice as likely to develop AD as those people without the variation. "We are hopeful our identification of MTHFD1L as a risk gene for Alzheimer's disease will help us to better understand how this disease develops and potentially serve as a marker for people who may be at increased risk," said co- author Adam Naj, Ph.D. "Identifying this gene is important because the gene is known to be involved in influencing the body's levels of homocysteine, and high levels of homocysteine are a strong risk factor for late-onset Alzheimer's disease," said Dr. Pericak-Vance. "In addition, variations of the MTHFD1L gene have been reported to possibly increase the risk of coronary artery disease. Since the function of blood vessels in the brain may affect Alzheimer's disease, this finding may also help us understand how homocysteine levels and blood vessel function in the brain affect Alzheimer's disease." Read more: redorbit.com


Vitamin C improves mood
Supplementation with vitamin C could improve the emotional state of hospitalized patients, according to new research. Read morenutraingredients.com
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