Spinal-fluid biomarkers
(can be predicted with up to 100 per cent)
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"The initiation of the Alzheimer's disease pathogenic process is typically unobserved and has been thought to precede the first symptoms by 10 years or more," the authors of the ADNI study published Monday wrote. But the fact that the biomarkers were present in more than one-third of cognitively normal subjects suggested to the researchers that "Alzheimer's disease pathology is active and detectable earlier than has heretofore been envisioned."
Scientists have been searching "in earnest" for biochemical markers of Alzheimer's Disease in body fluids since the late 1990s, when a working group outlined the ideal biochemical markers for the disease, an editorial in the same issue of the Archives of Neurology said. Among other things, biomarker tests should be more than 80-per cent accurate for detecting Alzheimer's, technically reliable and reproducible, noninvasive, simple to perform and inexpensive.
The test used by De Meyer and colleagues met most of the criteria, said the editorial. But, it added: "Whether it is noninvasive or not is in the eye of the beholder: performing a lumbar puncture is no more invasive than other outpatient procedures such as endoscopies that millions of Americans tolerate each year." An estimated 37 million people worldwide, including 5.3 million in the United States, live with dementia, with Alzheimer's disease causing the majority of cases, according to the World Health Organization (WHO). Read more: canada.com
Novel food approval for a wood extract
A Russian firm has applied for novel food approval for a wood extract, which it says has antioxidant, anti-inflammatory and cardiovascular benefits. Read more: nutraingredients.com
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