New target for fighting Alzheimer's
(an early breakthrough for treatment)
(an early breakthrough for treatment)
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French researchers said Tuesday they had found a promising new target in the fight against Alzheimer's, the debilitating brain disease that causes irreversible memory loss and dementia. In laboratory experiments, a team led by Etienne-Emile Beaulieu of the French National Institute of Health and Medical Research (INSERM) uncovered what could prove a critically important interaction between two types of proteins.
The telltale symptoms of Alzheimer's and other neurodegenerative diseases have been linked to an overabundance in the brain of the tau protein. Beaulieu and colleagues discovered that another protein known as FKBP52, which also helps regulate immune responses, may slow or prevent that damaging accumulation. "It's an 'anti-tau' weapon located within the cells," Beaulieu said at a press conference in Paris. "We want to boost the efficiency of this weapon and find pharmaceutical ammunition -- new drugs -- to accelerate its action so that it can destroy unwanted tau," he told journalists.
The study was published this week in the US Proceedings of the National Academy of Sciences. Developing such a drug may take a long time, he said, "but in two or three years we should be able to find a way to at least make an early diagnosis." Read more: canada.com
Omega-3 study doses were too low for heart protection
The Global Organization for EPA and DHA Omega-3 (GOED) has said dosage levels were too low in a study suggesting EPA/DHA enriched spreads do not protect heart attack sufferers from further cardiac events. Read more: nutraingredients.com
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