Active ingredient in garlic extract and Alzheimer's disease
(multi-faceted nature of this disease)
(multi-faceted nature of this disease)
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The proportion of elderly population with Alzheimer’s disease is increasing worldwide. Three main features of this disease are: deposition of amyloid-beta peptides causing brain inflammation that damages neurons; chemical changes in tau protein affecting cellular transport via microtubules; and loss of neurons releasing acetylcholine that controls the functions of heart and muscles. The available drugs that target single steps in the progression of the disease can provide some symptomatic relief, but these drugs cannot control or cure the disease. “We hypothesize that an agent effective in modulating multiple pathological pathways could be an appropriate therapeutic agent in preventing and restricting Alzheimer’s disease progression.” Natural substances such as garlic and turmeric are tested because of their low costs, easy availability and fewer possible side effects. Garlic affects different aspects of the progression of the disease, showing the potential to be a possible cure for Alzheimer’s disease. A drug will have to address all these aspects of the pathology to prove to be successful as a treatment for Alzheimer’s disease. The ingredients present in AGE seem to reduce the chemical changes in proteins affecting transport in brain cells, and also affect many aspects of interconnected chemical pathways to reduce swelling in the brain. While more research is needed, remedies such as garlic and curcumin (turmeric) are potentially beneficial in restricting the symptoms of Alzheimer’s disease. Continue to read: fyiliving.com
Green tea compound blocks weight gain
The green tea extract epigallocatechin gallate (EGCG) may slow weight gain by limiting fat absorption, according to new research. Read more: nutraingredients.com