Wednesday, December 28, 2011

What Causes Alzheimer’s?

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(  to attack this disease by reducing amyloid plaques  )
In neuroinflammation we had a viable suspect—and a potential therapeutic target—which everyone seemed to be ignoring. A 1994 report by John Breitner at Johns Hopkins showed that among genetically predisposed identical twin pairs who did not show same-age Alzheimer’s onset, use of nonsteroidal anti-inflammatory drugs (NSAIDs) by one of the twins was associated with a several-year delay in the onset of Alzheimer’s.11 This was not an isolated study; several years later, a Dutch study comparing a large group of Alzheimer’s patients who were taking NSAIDs for other ailments to those who were not showed a reduced risk or delayed onset of Alzheimer’s disease—as calculated by the overall risk for the disease per year of life—of almost one-half. Then in a 2008 report from the Department of Veterans Affairs on 50,000 Alzheimer’s patients and 200,000 control patients, researchers showed that those who took ibuprofen for as long as five years had a reduced Alzheimer’s risk of almost one-half. A more direct approach in a clinical trial (ADAPT) of NSAIDs, including naproxen and celecoxib, was stopped after about 24 months because of drug safety concerns. However, observations that continued for two more years revealed a protective effect of one of the drugs, naproxen, when started before the onset of symptoms and taken for more than two years. (the-scientist.com)
As Alzheimer's sufferers experience a gradual decline in their mental state, caregivers can do little but watch this devastating disease rob them of their memories and functional abilities. The emotional heartbreak and financial burden on family members and other caregivers can be overwhelming. This is why we need to do more research, and why we are asking for your help. Continue to readdonate




2011. The year that was

From health claims to heated herbal disputes to stressed tomato antioxidants, microflora revelations and cranberry wars, 2011 was another eventful year in the European healthy foods and supplements space. Read morenutraingredients.com 

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Погода в Беларуси


Posted YVN (AMYLOID @ PHOTO). 

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