ExonHit Presents New Data on Alzheimer's
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A novel mechanism of action when compared to existing Alzheimer's disease therapeutics: it stimulates the a-secretase pathway, thus enhancing the production of the procognitive and neuroprotective sAPPa fragment of APP (Amyloid Precursor Protein). Since the stimulation of the a-secretase pathway is to the detriment of Aß amyloid peptide production, EHT 0202 potentially reduces toxic Aß plaque formation. Phase I studies demonstrated good tolerability of EHT 0202 in both young and elderly healthy volunteers. Preclinical studies have shown that EHT 0202 protects cortical neurons against Aß42-induced toxicity and that this neuroprotection is associated with sAPPa induction. EHT 0202 has also demonstrated procognitive properties in several animal models: age-related memory impairment and scopolamine-induced amnesia. Procognitive properties of EHT 0202 were recently published in an aged rat model.To get more: 4g-wirelessevolution.tmcnet.com
Science highlights promise of prebiotics for weight management
Prebiotic fibres may beneficially modify bacterial populations in our guts and aid weight management, with “promising effects also shown in humans”, says a new review of the science. ...nutraingredients.com
What the World Eats ~~~~~~~~~~~ Belarusian Pork and Potato Pie
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