The implicated blood proteins in people with Alzheimer’s

( to determine the pathology of disease in the brain )

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A simple blood test may soon be able to “predict Alzheimer's disease up to 10 years before symptoms appear”, says The Daily Telegraph. The newspaper says researchers have discovered that a rise in levels of a protein called clusterin may be an early sign of the disease.
The observational and laboratory studies that lie behind this report have been well conducted and reported, and its authors have found clusterin levels are linked to cognitive decline, the severity of disease in people with Alzheimer’s and the rate of clinical progression of Alzheimer’s disease. However, the researchers do not suggest that this may be used to diagnose disease, at least not yet. In fact they say that their study does not support the clinical use of clusterin levels as a standalone biomarker for Alzheimer’s disease. These are interesting findings, but early ones that will lead to more research about protein markers of this disease rather than directly to a clinical test.
The study was carried out by researchers from King’s College London and a number of medical and academic institutions across the world. The study was funded by the European Union and authors received funding from the Alzheimer’s Research Trust, the UK National Institute for Health Research, the Biomedical Research Centre for Mental Health, the Bupa Foundation and the Alzheimer’s Society. The research was published in the peer-reviewed medical journal, Archives of General Psychiatry. Read more: lep.co.uk

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