A technique to identify individuals at risk for Alzheimer’s
(the beginning stages)
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The sizes of nine critical regions in the brain may serve as predictors for Alzheimer’s disease, according to a new study led by Bradford C. Dickerson, associate professor of neurology at Harvard Medical School. The study builds on Dickerson’s prior research, which observed that these nine regions exhibited shrinkage in Alzheimer’s patients.
Aly Negreira, a research assistant at Dickerson’s lab, said that this past work “highlighted certain nodes in the brain that shrink preferentially if you are diagnosed with Alzheimer’s disease.” The latest research indicates that cognitively normal individuals with smaller measurements in these regions are more likely to be afflicted with Alzheimer’s in the future. The researchers tracked 65 subjects, all initially cognitively normal, for approximately a decade. When the study concluded, six of the eleven subjects with the smallest brain measurements had developed Alzheimer’s.
Negreira said these patients were “asymptomatic about a decade before they actually converted to dementia.” Conversely, all nine subjects with the largest measurements remained cognitively normal ten years into the study. Such results suggest that this method could one day serve as an early diagnostic technique for Alzheimer’s, according to Dickerson. Read more: thecrimson.com
A prescription medical food for the dietary management of Alzheimer’s
Ann Arbor-based Adeona Pharmaceuticals reported top-line results from its clinical study evaluating reaZin for the dietary management of Alzheimer’s disease and mild cognitive impairment. Read more: detroit.cbslocal.com
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