Alzheimer's: when proteins acting together
(truncated tau)
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There are two proteins in the brain that become abnormal when a person has Alzheimer's disease. These two proteins are beta amyloid and tau. When combined, the result is problems in the parts of the brain cells that make energy for the cells. These findings are a result of new research and have been published online in " Neurobiology of Aging. "
This research has scientists thinking that the abnormal forms of beta amyloid and tau may work together to destroy brain cells. Beta amyloid and tau make up plaques and tangles in the brain of a person with Alzheimer's disease. This information is part of a number of findings from a few different laboratories that are studying a part of the cell called the mitochondria. Many researchers believe problems with the mitochondria may be responsible for many abnormal brain conditions like Alzheimer's disease.
The mitochondria of the cell are the energy producers inside all cells, including the neurons. The mitochondria are always working to produce the energy cells need to stay alive. Also, the mitochondria are like the control center of the cells and are in charge of many functions like keeping the amount of calcium in a cell at normal levels. If there is something wrong with a cell's mitochondria, it cannot make enough energy to stay alive. In addition faulty mitochondria make the cell unable to use calcium correctly and cause cell damaging molecules to be released. These types of problems may be happening in those with Alzheimer's disease. The result is that the nerve cells in the brain exhibit abnormal function. Continue to read: associatedcontent.com
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