A discovery in the effort to better understand Alzheimer's
(estrogen will induce)
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A research team led by Dr. Andrea LeBlanc believes it has isolated an enzyme that could be the root cause of the disease that afflicts one in 11 Canadians.
If indeed the enzyme – called Caspase-6 – is found to be the cause it could help doctors diagnose the disease far earlier in its progression, which could at least allow the opportunity to try different therapies in an effort to slow the disease down.
The current "amyloid theory" of Alzheimer's disease fingers amyloid beta (Abeta) as the fundamental cause of the disease, a news release from the hospital states. Abeta forms what is called "senile plaques" on the brains of Alzheimer's sufferers.
LeBlanc's theory is that Abeta is an effect, and not a cause of the disease, and that it is in fact the presence of the Caspase-6 enzyme that triggers the onset of Alzheimer's.
"Where we saw the active enzyme is the area of the brain that is known to first be affected by Alzheimer's disease," LeBlanc told CTV Montreal's Paul Karwatsky.
LeBlanc's findings suggest the brains of people who succumbed to Alzheimer's had a high level of Caspase-6, while there is virtually none in the brains of older people who did not have the disease or those under 45. LeBlanc also found that older people who did not have Alzheimer's but had signs of memory loss also had elevated levels of the enzyme. Read more: montreal.ctv.ca
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The link between gut and brain may extend to reducing stress, as data from animal and human studies show a reduction in anxiety following probiotic supplementation. Read more: nutraingredients.com
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