Experimental vaccine against Alzheimer's
(DNA vaccine)
Please Help Support Alzheimer's Research Today!
Your Alzheimer's donation will help billions live without it.
Compared with similar so-called DNA vaccines that the UT Southwestern researchers tested in an animal study, the new experimental vaccine stimulated more than 10 times as many antibodies that bind to and eliminate beta-amyloid. The results appeared in the journal Vaccine.
Future studies will focus on determining the safety of the vaccine and whether it protects mental function in animals, said Dr. Roger Rosenberg, director of the Alzheimer's Disease Center at UT Southwestern and senior author of the study.
"The antibody is specific; it binds to plaque in the brain. It doesn't bind to brain tissue that does not contain plaque," Dr. Rosenberg said. "This approach shows promise in generating enough antibodies to be useful clinically in treating patients."
A traditional vaccine – an injection of beta-amyloid protein itself into the arm – has been shown in other research to trigger an immune response, including the production of antibodies and other bodily defenses against beta-amyloid. However, the immune response to this type of vaccine sometimes caused significant brain swelling, so Dr. Rosenberg and his colleagues focused on developing a nontraditional DNA vaccine. Read more: eurekalert.org
Antioxidants, prebiotics and probiotics as functional foods
The term "functional foods" comprises some bacterial strains and products of plant and animal origin containing physiologically active compounds beneficial for human health and reducing the risk of chronic diseases. Among the best known functional compounds probiotics, prebiotics and natural antioxidants should be given as examples. These substances can be obtained by biotechnological methods and by extraction from plant or animal tissues. Read more: actabp.pl
No comments:
Post a Comment